What Does p62 Mean?
Keap1 also reversibly translocates into the p62-gels in the p62-binding dependent style to activate the transcription factor Nrf2. Mice deficient for Atg8-conversation-dependent selective autophagy present that impaired turnover of p62-gels leads to Nrf2 hyperactivation in vivo. These effects show that p62-gels aren't very simple substrates for aut